Leading the way.

PRESIDENT & CEO

Mr. Fallon is President, CEO and co-Founder of Promontory Therapeutics. He is a highly respected leader with decades of global transactional and strategic leadership. He is former Chairman & CEO of The Korea Exchange Bank, a large publicly traded company, and prior to that he ran all of Asia-Pacific for JP Morgan Chase.

He holds a BA in Mathematics from Ohio University, and an MBA from Harvard Business School. Mr. Fallon is also Chairman Emeritus of The Council on International Educational Exchange (CIEE), and is a member of The Council on Foreign Relations.

EXECUTIVE VICE PRESIDENT & COO

Mr. Price is Executive Vice President, Chief Operating Officer and co-Founder of Promontory Therapeutics, and has been responsible for strategy and operations across the company's activities since inception. He was named a 2022 Emerging Pharma Leader by Pharmaceutical Executive.

Mr. Price negotiated the original license for the company's PT-112 development program, and helps to oversee clinical and translational research and development, and manufacturing. He is further responsible for the company's clinical trials collaboration jointly with Pfizer and Merck KGaA, Darmstadt, Germany, and its CRADA with the National Cancer Institute (NCI) .

He previously held research and managerial roles in the NGO and non-profit sectors working in the US and Germany. He holds an AB from Princeton University, graduating summa cum laude and Phi Beta Kappa, and earned his MBA from Columbia Business School, where he was a Chazen Society Fellow in International Business.

EXECUTIVE VICE PRESIDENT & CMO

Dr. Johan Baeck is an experienced industry clinician with deep expertise in oncology clinical development. Dr Baeck’s focus over the last years has been on the development of novel therapeutic approaches in oncology, specializing in small molecules, immunotherapy and biologic agents for the treatment of solid tumors and hematologic malignancies.

Dr. Baeck has held roles of increasing leadership responsibility at several large (such as Novartis and Abbott) as well as smaller biotech companies in commercial, clinical development and medical affairs roles. Prior to joining Promontory Therapeutics, Dr. Baeck served as Senior Vice President of Clinical Development and Medical Affairs at Jounce Therapeutics.

Dr. Baeck completed his Medical Degree in Leuven, Belgium and was a practicing physician in Belgium before transitioning to the pharmaceutical industry.

SVP, RESEARCH & DEVELOPMENT

Dr. Ames is Senior Vice President of Research & Development at Promontory Therapeutics, and leads the company's translational research efforts globally across multiple institutions.

Dr. Ames received his BS with high distinction in Biology and Biotechnology from Worcester Polytechnic Institute, and earned his doctorate in Molecular, Cellular and Developmental Biology from Yale University, where he focused on Nucleic Acid Biochemistry. Most recently he was a post-doctoral fellow at University of California Berkeley, focusing on Commercial Applications of Yeast Genetics.

VP, STRATEGY & OPERATIONS

Ms. Raphael is Vice President of Strategy & Operations, responsible for oversight and development of Promontory’s strategic commercial plan. She previously worked at Intercept Pharmaceuticals where she was the Chief of Staff to the President of US Commercial, and was a member of the Strategic Marketing team. Prior to that, she worked at Celgene in a variety of roles, including program management for early development, marketing for Revlimid®, and early commercialization at Celgene Cellular Therapeutics.

She graduated summa cum laude from Tufts University with a dual major in Civil and Biomedical Engineering, received her MS in Biomedical Engineering from Columbia University, and also earned her MBA from Columbia Business School.

SENIOR MEDICAL DIRECTOR

Dr. O’Donnell is Senior Medical Director at Promontory. He focuses on patient eligibility, enrollment and clinical case managements.

Dr. O’Donnell comes to the Company from the Geisel School of Medicine at Dartmouth, where he was an Associate Dean at the medical school and senior scholar at the C. Everett Koop Institute, and held the Elizabeth DeCamp McInerney endowed chair as a Professor of Medicine and Psychiatry. He was chief of oncology at the Dartmouth affiliated White River Junction VA Hospital, and a member and former associate director of the Norris Cotton Cancer Center. He has had extensive experience in clinical oncology, especially involving the cancers of most interest to Promontory Therapeutics, and has extensive clinical trials experience with CALGB, RTOG, VA Cooperative Studies and locally initiated Dartmouth protocols. He is past president of the American Association for Cancer Education, past editor of its Journal of Cancer Education and recipient of its highest award, the Margaret Hay Edwards Medal for achievement in cancer education. Joe previously served on the Company’s Scientific Advisory Board since inception.

He graduated with an A.B. in biology summa cum laude from Harvard College and an MD from Harvard Medical School. He did his internal medicine training at Dartmouth and his oncology training as a clinical associate at the National Cancer Institute. He is board certified in Internal Medicine and Medical Oncology.

VP, CHEMISTRY MANUFACTURING & CONTROLS

Dr. Shea is Vice President of Chemistry, Manufacturing and Controls (CMC) and is responsible for all technical operations including manufacturing, analytical development and supply chain. Throughout her career, she has held a number of roles of increasing leadership responsibilities at both small and large companies including Head of CMC at AMAG Pharmaceuticals and the Head of the Catalysis Laboratory at Johnson Matthey Pharma Services. Her oncology experience includes her drug substance program leadership for brigatinib (Alunbrig ®) at Ariad Pharmaceuticals. Prior to joining Promontory, she was VP, Head of CMC at Saniona, a Danish rare disease company.

Dr. Shea graduated with a BA in Chemistry from the College of the Holy Cross and a PhD in Organic Chemistry from Dartmouth College, and held a post-doctoral fellowship at Texas A&M University.

PHARMACOKINETICS

Dr. Graham has been involved in drug development for over 25 years and is a specialist in PK /PD analysis, and serves as Lead Pharmacokineticist for Promontory Therapeutics' drug development efforts. He began his career at Sanofi-Synthelabo, in both the UK and the US. Dr. Graham later served as Director of Pharmacokinetics at Centocor Corporation, a Johnson and Johnson Company; VP of Research and Development at Gemin X Biotechnologies; and VP of Development and Regulatory Affairs at Tetralogic Pharmaceuticals.

He founded PKPD Bioscience in 2004, which was later integrated into Kinderpharm, a pediatric drug development company he had also founded in 2014. Dr. Graham serves as President & CEO of both entities. With his extensive R&D experience with both small molecules and protein therapeutics from IND to NDA/BLA, Dr. Graham has been involved in numerous regulatory filings in the US, Japan and Europe for a wide variety of products including Oxaliplatin, Rasburicase, Mitoguazone, Tirapazamine, Alfuzosin, Birinapant, Stelara and Remicade.

He is a graduate of Leeds University, England where he earned his BSc in Pharmacology and Microbiology, and went on to earn his PhD from the University of London at the Institute of Cancer Research, Royal Marsden Hospital in 1990. He is the author of a text book on the pharmacokinetics of cancer chemotherapy and has substantial publication record in the area of pharmacokinetics, drug metabolism and clinical pharmacology.

CMC REGULATORY AFFAIRS

Dr. Eckrich is an experienced Chemistry Manufacturing and Controls (CMC) executive with 33 years of experience in the pharmaceutical industry, primarily with Eli Lilly and Company. His accomplishments include NDA submissions for Loracarbef, Gemcitabine, Raloxifene and Tadalafil. He also managed Eli Lilly’s European development center in Mont Saint Guibert, Belgium, leading the growth of the premier small molecule process R&D group in the US pharma industry during the early 2000s, and established a network of more than 30 company relationships for Lilly’s development outsourcing capability.

In 2014, Dr. Eckrich founded Eckrich consulting services, LLC, which provides expertise to the chemical and pharmaceutical industries in chemical process development and manufacturing, with a focus on synthetic organic chemistry. Dr. Eckrich earned a doctorate in Chemistry from Harvard University in 1984, studying with Professor E. J. Corey, the 1990 Nobel Laureate in Chemistry.

Daniel D. Von Hoff, M.D., F.A.C.P. is currently Physician in Chief and Distinguished Professor at the Translational Genomics Research Institute (TGen) in Phoenix, Arizona. He is also Chief Scientific Officer for HonorHealth Clinical Research Institute and Medical Director of Research at McKesson Specialty Health, US Oncology Research. He is also Professor of Medicine, Mayo Clinic Scottsdale, AZ.

Dr. Von Hoff’s major interest is in the development of new anticancer agents, both in the clinic and in the laboratory. He and his colleagues were involved in the beginning of the development of many FDA approved agents we now use routinely, including: mitoxantrone, fludarabine, paclitaxel, docetaxel, gemcitabine, irinotecan, nelarabine, capecitabine, lapatinib, vismodegib, nab-paclitaxel, nal-IRI, and others. His clinical trial work has led to the approval of 3 of the 4 drugs approved by the FDA for treatment of patients with advanced pancreatic cancer. At present, he and his colleagues are concentrating on the development of molecularly targeted therapies particularly for patients with advanced pancreatic cancer.

Dr. Von Hoff has published more than 675 papers, 140 book chapters and over 1170 abstracts. Dr. Von Hoff received the 2010 David A. Karnofsky Memorial Award from the American Society of Clinical Oncology for his outstanding contributions to cancer research leading to significant improvement in patient care.

Dr. Von Hoff was also a Founder of Ilex Oncology, which obtained FDA approval for two new anti-cancer agents: Campath for the treatment of patients with CLL and multiple sclerosis; and Clofarabine for the treatment of children with Leukemia. The company was acquired by Genzyme.

Dr. Von Hoff was appointed to President Bush’s National Cancer Advisory Board in 2004-2010. Dr. Von Hoff is the past President of the American Association for Cancer Research (the world’s largest cancer research organization), a Fellow of the American College of Physicians, and a member and past board member of the American Society of Clinical Oncology. He is also proud to have been a mentor and teacher for multiple medical students, medical oncology fellows, graduate students, and post-doctoral fellows.

Dr. Karp graduated from Harvard College in 1969, and received his medical degree from the Duke University School of Medicine in 1973. He was awarded numerous postgraduate and clinical fellowships, including at the Sidney Farber Cancer Institute in Boston from 1978-80. Dr. Karp’s focus at MD Anderson Cancer Center is on new drug development in the phase I facility, as well as medical graphics and informatics, and cancer chemoprevention.

Dr. Karp is proud to have had a role in the early clinical trials of Epirubicin, the Taxanes, and the new Targeted Oral Inhibitors of the Epidermal and Vascular Growth Factor Receptors, as well as in recent studies of the Insulin Growth Factor Receptor (IGFR).

Dr. Galluzzi is a world-renowned scientist who has been honored as one of the most highly cited researchers in the field of Immunology, Molecular Biology and Genetics, with over 500 publications. His pioneering research included the seminal characterization of immunogenic cancer cell death (ICD) and the adaptive immune response. Dr. Galluzzi holds multiple professorial roles, including at Weill Cornell Medical College as head of the Galluzzi Lab and Assistant Professor of Cell Biology in Radiation Oncology, and at Yale School of Medicine as Assistant Professor Adjunct, and a faculty appointment at University of Rome “La Sapienza”. He is also an associate director of the European Academy for Tumor Immunology, and founding member of the European Research Institute for Integrated Cellular Pathology. Dr. Galuzzi completed his post-doctoral training at the Gustave Roussy Comprehensive Cancer Center in France, after receiving his PhD from the University Paris Sud.

Dr. Noel has had thirty years of experience in pharmaceutical drug development. She currently serves as Chief Operating Officer of Collaborative Medicinal Development, a privately held drug development group focused on neuro-degenerative diseases. She was previously Co-founder and COO of OncoEthix SA, which was sold to Merck in 2014, and before that was Co-Founder and VP of Business Development of Oncology Therapeutics Network, which was sold to Bristol Myers Squibb.

Earlier in her career she was director of Biologics R&D at Abbott. Dr. Noel holds a PhD in Biophysics from the University of Michigan, and completed post-doctoral studies at UCLA under a fellowship from the National Institutes of Health.

Dr. Jimeno is a seasoned medical oncologist, who also holds a PhD from the University of Barcelona. He has had a focus in drug development for over twenty years. Dr. Jimeno served as Chief Medical Officer at Promontory Therapeutics, in which role he was instrumental in the early clinical development of PT-112, and joins the Scientific Advisory Board in order to maintain his involvement in the program. He was formerly VP of Clinical and Scientific Development at PharmaMar, responsible for the integrated development of Yondelis®, which is approved in the US, the EU, Japan, and more than 60 other countries for the treatment of ovarian cancer and sarcoma; the development of Aplidine® in advanced cancer patients; and the design of the pivotal study in multiple myeloma, which has had its first approval in Australia.

His prior industry roles include work at Farmitalia Carlo Erba and US Biosciences, where he focused on novel compounds in the anthracycline and anti-metabolite therapeutic classes. Most recently, Dr Jimeno was co-founder and CEO of Pangaea Biotech, a cancer diagnostics company focused on personalized medicine, where he was involved in the development of the EGFR mutation diagnostic approved by the FDA for use in non-small cell lung cancer (NSCLC) cancer patients. Dr. Jimeno has published over 100 papers in peer review journals on cancer and is a guest lecturer in immunology at The University of Zaragoza in Spain.

Dr. Scher, D. Wayne Calloway Chair in Urologic Oncology, has dedicated his career to the co-development of targeted therapies and biomarkers such as circulating tumor cells (CTCs) which can be used to assess treatment efficacy, guide treatment selection for the individual patient and improve the way drugs are evaluated in the clinic, accelerating regulatory approvals. During his 25-year tenure as the Chief of the Genitourinary Oncology Service at Memorial Sloan Kettering Cancer Center (MSKCC) he led international efforts to standardize the design and analysis of phase II prostate cancer trials (PCWG2, PCWG3) and helped elucidate key molecular and genetic features of the disease, translating these insights into the clinic by leading early phase and phase III registration trials of abiraterone acetate and enzalutamide which are now FDA approved.

In his current roles—Head of MSKCC’s Biomarker Development Program; Member and Attending Physician, Genitourinary Oncology Service, Department of Medicine at MSKCC; and Professor of Medicine at the Weill Cornell Medical College—Dr. Scher applies the same principles used in developing drugs to blood and imaging-based biomarkers in a regulatory context to better inform diagnostic and therapeutic decisions so that patient outcomes are improved.

Dr. Scher serves as the principal investigator of the NIH Specialized Program of Research Excellence (SPORE) in Prostate Cancer at MSKCC and the Department of Defense-sponsored Prostate Cancer Clinical Trials Consortium (PCCTC), and has received the 2015 AACR Team Science Award for his multidisciplinary work developing AR inhibitors, the Donald S. Coffey-Prostate Cancer Foundation Physician Scientist award and the Chemotherapy Foundation Ezra Greenspan Award. Dr. Scher was elected to the Association of American Physicians and named a Fellow of the American Society of Clinical Oncology (ASCO).

Mr. Fallon is Chairman of the Board of Directors. He is a co-founder of Promontory Therapeutics and serves as President & CEO.

Mr. Caouette is Founding Chairman of Channel Capital, which provides technology-enabled financing to corporates operating in global markets, and was previously Vice Chairman of MBIA Insurance Corp., and Founder and CEO of CapMac Holdings. He received his MBA from the UC Berkeley Haas Business School, where he has also served as Adjunct Professor in entrepreneurship.

Mr. Espig is the CEO of Nicola Mining Inc. (TSX.V: NIM) and Sweet Earth Holdings (CSE: SE). He sits on the board of several public and private companies, as well as charitable organizations. He was previously Vice President of the Special Situations Group of Goldman Sachs Japan, and Vice President of Olympus Capital, a New York private equity firm. He holds a BA from the University of British Columbia, where he was a member of its National Champion football team, and an MBA from Columbia Business School, where he was an International Chazen Society Fellow.

Dr. Leong is chief executive and director of Bunker Hill Developments, Inc., and of Persis Corporation, both real estate development companies. She is a Trustee of the University of Hawai’i Foundation, and former Chief Pathologist of the Metropolitan Hospital in Manila, Philippines.

Sebastian Guth is a multi-national executive with 20+ years of experience in pharmaceuticals and medical technology across three continents, with proven results in both strategic and operational leadership roles at the most senior level. He serves as President of Bayer U.S. and President, Pharmaceuticals, North America. Prior to that, Dr. Guth served as Executive Vice President and Chief Marketing Officer of Bayer’s global pharmaceuticals, responsible for Xarelto® and Eylea® among other products, and was previously Chief Executive Officer of Bayer Turk, Istanbul and President & CEO of Bayer Yakuhin, Osaka.

He is currently a member of the Board of the Pharmaceutical Research and Manufacturers of America (PhRMA), the Biotechnology Innovation Organization (BIO), and of Children’s Aid. He holds an MBA from the WHU Otto Beisheim Graduate School of Management and a PhD in Management Sciences from Berlin University of Technology in Germany.

Mr. Price is a co-founder of Promontory Therapeutics and serves as Executive Vice President and Chief Operating Officer. In addition, he represents one of the founding investors, Absaroka Partners LLC.

Mr. Stuckey is Chairman Emeritus and former CEO of RSA Security, which was acquired by EMC Corp in 2006. He also served as a Director of Matrix One until its acquisition in 2006 by Dassault Systems. He is Chairman Emeritus of the Ohio University and Ohio University Foundation Board of Trustees.

Dr. Sunderland is Chairman of Adinvest AG, a Swiss family office. He has extensive experience in private equity investments, including the digital economy and the life sciences. Dr. Sunderland has served on the boards of numerous public and private companies including Leica plc, Saurer AG and Xing AG, the leading professional networking platform in the German speaking world that he chaired for many years. He was previously executive director of Swiss Bank Corporation Intl in London and CEO of Elders Finance and Investment Co. in Australia. Dr. Sunderland holds a BSc and MSc from Imperial College, London, and a doctorate from the Swiss Federal Institute of Technology (ETH).

Ms. Tallett has more than 35 years of experience across strategic leadership and operational roles in worldwide biopharmaceutical companies. She was Principal of Hunter Partners, which advised Promontory Therapeutics early in its development. Previously, she served as President and CEO of Transcell Technologies Inc., and as President of Centocor Pharmaceuticals, which was acquired by Johnson and Johnson in 1999. Earlier in her career she was a member of the executive committee of Parke-Davis. In addition to serving on the Promontory Board of Directors, Ms. Tallett currently serves on the boards of Moderna Inc., Anthem, Inc., Qiagen, Inc., and Meredith Corp.